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課程名稱 |
人腦映像方法
Human Brain Mapping Methods |
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開課學期 |
103-2 |
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授課對象 |
工學院 醫學工程學研究所 |
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授課教師 |
林發暄 |
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課號 |
Biomed7086 |
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課程識別碼 |
548 M1300 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期四5,6,7(12:20~15:10) |
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上課地點 |
共206 |
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備註 |
總人數上限：20人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1032Biomed7086_ |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
Course Schedule
1 Introduction
2 Functional neural systems
2.1 Cellular electrophysiology
2.2 System neuroanatomy
3 Neurovascular coupling
4 Electrophysiological measurements (Magnetoencephalography)
4.1 Physiological origin
4.2 Forward problem
4.3 Inverse problem
5 Hemodynamic measurements (functional MRI)
5.1 Physiological origin
5.2 Contrast mechanisms (BOLD, flow/volume)
5.3 Experiment design
5.4 Pre-processing
5.5 Statistical analysis
6 Other measurements
6.1 Structure
6.2 Metabolism (MR spectroscopy) |
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課程目標 |
This course focus on the introduction of modern non-invasive human neuroimaging facilities, including but not limited to, structural magnetic resonance imaging (MRI), functional magnetric resonance imaging (fMRI), MR spectroscopic imaging, and magnetocephalography (MEG). We will also include a very brief introduction to the cellular and system level neuroscience before presenting individual imaging methods. We wish to bring you a general concept of neuroimaging methods as well as their features, advantages, and limitations. |
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課程要求 |
無 |
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預期每週課後學習時數 |
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Office Hours |
另約時間 |
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指定閱讀 |
無 |
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參考書目 |
Brain Mapping: The Methods (ISBN: 0126925402) Arthur W. Toga, John C. Mazziotta
Academic Press; 1st edition (January 15, 1996)
Principles of Neural Science (ISBN: 0838577016) Eric R. Kandel, James H. Schwartz, Thomas M. Jessell
McGraw-Hill Medical; 4 edition (January 5, 2000)
An Introduction to Functional Magnetic Resonance Imaging: Principles and Techniques (ISBN:
0521002745) R. B. Buxton
Cambridge University Press; Har/Cdr edition (December 15, 2001)
Functional Magnetic Resonance Imaging (ISBN: 0878932887) Scott A. Huettel, Allen W. Song, Gregory
McCarthy
Sinauer Associates; Har/Cdr edition (April 1, 2004)
The Human Brain: An Introduction to Its Functional Anatomy (ISBN: 0323013201) John Nolte
Mosby; 5 edition (January 15, 2002) |
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
Course Participation |
30% |
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2. |
Quizzes & Homework |
30% |
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3. |
Final Report |
40% |
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週次 |
日期 |
單元主題 |
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第1週 |
2/26 |
introduction; history; time and space; (核心2,4) |
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第2週 |
3/05 |
system neuroanatomy (核心2,4) |
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第3週 |
3/12 |
magnetic resonance imaging (核心2,4) |
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第4週 |
3/19 |
diffusion MRI and structural connectivity (核心2,4) |
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第5週 |
3/26 |
MRI and echo-planar imaging (核心2,4) |
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第6週 |
4/02 |
春假 |
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第7週 |
4/09 |
hemodynamic measurements: perfusion (核心2,4) |
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第8週 |
4/16 |
metabolic measurements: MR spectroscopy (核心2,4) |
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第9週 |
4/23 |
Transcranial magnetic stimulation (TMS) (核心2,4) |
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第10週 |
4/30 |
metabolic measurements: positron emission tomography (PET) (核心2,4) |
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第11週 |
5/07 |
magnetoencephalography (MEG) and electroencephalography (EEG) I (核心2,4) |
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第12週 |
5/14 |
magnetoencephalography (MEG) and electroencephalography (EEG) II (核心2,4) |
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第13週 |
5/21 |
final report 1 |
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第14週 |
5/28 |
final report 2 |
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第15週 |
6/04 |
課程期末問卷 (修課人數=9, 問卷回收率=67%) |
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